Search results for "Precocious pseudopuberty"

Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour

2011

Aim:  To analyse the urinary steroid metabolome in a boy who had true precocious puberty after a Leydig cell tumour. Method:  Case report and detailed description of clinical and metabolic findings in a 7-year-old-boy with a Leydig cell tumour. Results:  Before surgery, the urinary steroid metabolome showed an activation of an alternative route to gonadal androgens independent of dehydroepiandrosterone (DHEA). After surgery, the boy entered true precocious puberty. Under leuprolide acetate treatment, clinical and laboratory findings normalized. Conclusion:  Central precocious puberty after precocious pseudopuberty may be more common than expected and should be considered in children with pe…